Linking nationwide health and social registry data to inform the policy for Tuberculosis contact tracing in Brazil.

Objectives Mitigating the socioeconomic determinants of Tuberculosis (TB) and systematic screening of contacts and high-risk groups are targets of The World Health Organization (WHO) End TB Strategy by 2035.Our aim was to link socioeconomic information to TB datasets to inform policy makers in Brazil and contribute to addressing current challenges.

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Immunoinformatics Design and Assessment of a Multiepitope Antigen (OvMCBL02) for Onchocerciasis Diagnosis and Monitoring

Onchocerciasis is a Neglected Tropical Disease that has a significant socioeconomic impact, especially in Sub-Saharan Africa.Numerous reports indicate that the Expanded Special Project for the Elimination of Neglected Tropical Diseases needs novel diagnostic tools before achieving its goal of successful elimination of onchocerciasis in Africa.The c

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Chasing behaviour and optomotor following in free-flying male blowflies: flight performance and interactions of the underlying control systems

The chasing behaviour of male blowflies after small targets belongs to the most rapid and virtuosic visually guided behaviours found in nature.Since in a structured environment any turn towards a target inevitably leads to a displacement of the entire retinal image in the opposite direction, it might evoke optomotor following responses counteractin

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The UBA-UIM domains of the USP25 regulate the enzyme ubiquitination state and modulate substrate recognition.

USP25m is the muscle isoform of the deubiquitinating (DUB) enzyme USP25.Similarly to most DUBs, data on USP25 regulation and substrate recognition is scarce.In silico analysis predicted three ubiquitin binding domains (UBDs) at the N-terminus: one ubiquitin-associated domain (UBA) and two ubiquitin-interacting motifs (UIMs), whereas no clear struct

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